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So understanding the biology alone didnt get us there, but it was absolutely necessary before we could move on to the next phase. Each new leap in understanding may not be prize-worthy in isolation, but with each one, the door cracked open wider, expanding the number of people who could benefit from GLP-1 and other gut-hormone-based treatments

Now, in the case of alcohol, the study demonstrates a causal effect of the drug, although, for the moment, only in people with obesity, so it is not yet generalizable to the entire population"

274,275 Therapeutic strategies targeting oxidative stress and mitochondrial dysfunction include using antioxidants like alpha-lipoic acid (ALA), which improves neuropathic symptoms and nerve conduction velocities in patients with DPN

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